Weltschmerz
Concise Oxford English Dictionary © 2008 Oxford University Press:
Weltschmerz /ˈvɛltˌʃmɛːts/
▶noun a feeling of melancholy and world-weariness.
– origin Ger., from Welt ‘world’ + Schmerz ‘pain’.
'Weltschmerz' also found in these Oxford entries:

