WordReference Random House Unabridged Dictionary of American English © 2017
ag•o•nist  (agə nist),USA pronunciation n. 
  1. a person engaged in a contest, conflict, struggle, etc., esp. the protagonist in a literary work.
  2. a person who is torn by inner conflict.
  3. Physiologya contracting muscle whose action is opposed by another muscle. Cf. antagonist (def. 3).
  4. Drugs[Pharm.]a chemical substance capable of activating a receptor to induce a full or partial pharmacological response. Cf. antagonist (def. 5).
  • Greek agōnisté̄s contestant, equivalent. to agó̄n agon + -istēs -ist
  • Late Latin agōnista
  • 1620–30

'agonist' also found in these entries:
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