antagonize


Concise Oxford English Dictionary © 2008 Oxford University Press:
antagonize /anˈtaɡənʌɪz/ (or antagonise)
verb
  • 1 make hostile.
  • 2 Biochemistry act as an antagonist of (a substance).
– origin C18 (in the sense ‘struggle against’): from Gk antagōnizesthai, from ant- ‘against’ + agōnizesthai ‘struggle’.
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