WordReference Random House Learner's Dictionary of American English © 2017
des•e•crate /ˈdɛsɪˌkreɪt/USA pronunciation   v. [ + obj], -crat•ed, -crat•ing. 
  1. to violate by treating with disrespect; defile:desecrated the building by painting swastikas on the walls.
des•e•cra•tion /ˌdɛsɪˈkreɪʃən/USA pronunciation  n. [uncountable]

WordReference Random House Unabridged Dictionary of American English © 2017
des•e•crate  (desi krāt′),USA pronunciation v.t.,  -crat•ed, -crat•ing. 
  1. to divest of sacred or hallowed character or office.
  2. to divert from a sacred to a profane use or purpose.
  3. to treat with sacrilege;
    profane.
dese•crat′er, dese•cra′tor, n. 
des′e•cration, n. 
  • de- + -secrate, modeled on consecrate 1665–75
    • 3.See corresponding entry in Unabridged defile, violate, dishonor, pollute, outrage.

'desecration' also found in these entries:
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