grief

Concise Oxford English Dictionary © 2008 Oxford University Press:
grief/ɡriːf/

▶noun

• 1 intense sorrow, especially caused by someone's death.

  ■ an instance or cause of intense sorrow.

• 2 informal trouble or annoyance.

– phrases
come to grief have an accident; meet with disaster.
good grief! an exclamation of surprise or alarm.

– origin ME: from OFr. grief, from grever (see grieve1).