spite

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Concise Oxford English Dictionary © 2008 Oxford University Press:
spite/spʌɪt/
noun a desire to hurt, annoy, or offend. verb deliberately hurt, annoy, or offend.
– phrases
in spite of without being affected by the particular factor mentioned.
in spite of oneself although one did not want or expect to do so.
– origin ME: shortening of OFr. despit ‘contempt’, despiter ‘show contempt for’.
'spite' also found in these Oxford entries:

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