WordReference English-Italiano Dictionary © 2014:

Principal Translations/Traduzioni principali
loco adjadjective: Describes a noun or pronoun--for example, "a tall girl," "an interesting book," "a big house." slang (crazy, insane)pazzo, folle agg
  matto agg
loco nnoun: Refers to person, place, thing, quality, etc. slang ([sb] who is insane)pazzo, folle nm
  matto nm
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WordReference English-Italiano Dictionary © 2014:

Compound Forms/Forme composte
in loco in loco
in loco parentis advadverb: Describes a verb, adjective, adverb, or clause--for example, "come quickly," "very rare," "happening now," "fall down." (in place of a parent)  (formale, giuridico)in loco parentis
 Teachers act in loco parentis while children are at school.
 L'avvocato di famiglia ha dovuto agire "in loco parentis" per la tutela del minore dato che i genitori erano irreperibili.
loco parentis loco parentis
loco weed nnoun: Refers to person, place, thing, quality, etc. (jimson, plant with toxic and hallucinogenic effects)astragalo nm
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