WordReference English-Italiano Dictionary © 2014:

Principal Translations/Traduzioni principali
of course advadverb: Describes a verb, adjective, adverb, or clause--for example, "come quickly," "very rare," "happening now," "fall down." (naturally, as might be expected)naturalmente, chiaramente, certamente, ovviamente avv
 Of course, I will need to know where you are going.
 Chiaramente devo sapere dove andrete.
of course interjinterjection: Exclamation--for example, "Oh no!" "Wow!" (yes, certainly)certo, certamente avv
 Of course you can go out for dinner!
 Certo che puoi uscire per cena!
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WordReference English-Italiano Dictionary © 2014:

Compound Forms/Forme composte
as a matter of course   (automaticamente)d'ufficio
But of course interjinterjection: Exclamation--for example, "Oh no!" "Wow!" (expressing polite consent)ma certo inter
course of action nnoun: Refers to person, place, thing, quality, etc. (procedure)linea d'azione nf
 The course of action chosen by her doctor was successful.
 La linea d'azione scelta dalla polizia ha dato i suoi frutti.
course of studies (high school, college)  (di studi)indirizzo nm
course of study nnoun: Refers to person, place, thing, quality, etc. (academic course)corso di studi, indirizzo nm
 I chose Classics as my course of study.
 Ho scelto un corso di studi scientifico.
course of study nnoun: Refers to person, place, thing, quality, etc. US (subject: major)corso di studi nm
   (scuola,università: corso)indirizzo nm
 I chose Classics as my course of study.
 Come corso di studi ho scelto lettere classiche.
course of things corso delle cose
course of time corso del tempo
course of treatment nnoun: Refers to person, place, thing, quality, etc. (therapy to cure [sth])terapia nf
in the course of nel corso di
in the course of   (nel corso)durante
in the course of business nel corso degli affari
in the course of events nel corso degli eventi
in the course of time advadverb: Describes a verb, adjective, adverb, or clause--for example, "come quickly," "very rare," "happening now," "fall down." (eventually)a tempo debito
  alla fine
matter of course conseguenza naturale
Of course not interjinterjection: Exclamation--for example, "Oh no!" "Wow!" (emphatic: Certainly not)certo che no! inter
of course! altro che!
Of course! Si capisce! escl
out-of-course fuori corso
over the course of preppreposition: Relates noun or pronoun to another element of sentence--for example, "a picture of John," "She walked from my house to yours." (during, throughout)nel corso di, durante prep
 We spend a huge amount on the car over the course of a year.
the course of events il corso degli eventi
throughout the course of preppreposition: Relates noun or pronoun to another element of sentence--for example, "a picture of John," "She walked from my house to yours." (all the way through)nel corso di
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