WordReference English-Spanish Dictionary © 2014:

Principal Translations
aniquilar
aniquilarse
vtrverbo transitivo: Verbo que requiere de un objeto directo ("di la verdad", "encontré una moneda").
(matar, destruir)  (bring to nothing)annihilate vtrtransitive verb: Verb taking a direct object--for example, "Say something." "She found the cat."
   (population, ethnic group)destroy, massacre, slaughter vtrtransitive verb: Verb taking a direct object--for example, "Say something." "She found the cat."
   (figurative: eliminate, get rid of)wipe out vtr phrasal sepphrasal verb, transitive, separable: Verb with adverb(s) or preposition(s), having special meaning, divisible--for example, "call off" [=cancel], "call the game off," "call off the game."
   (slang)waste vtrtransitive verb: Verb taking a direct object--for example, "Say something." "She found the cat."
 Aniquiló a todo hombre que vivía en el poblado.
 He annihilated every man that lived in the village.
aniquilar vtrverbo transitivo: Verbo que requiere de un objeto directo ("di la verdad", "encontré una moneda"). (anular la personalidad)  (personality, quality:)destroy, crush vtrtransitive verb: Verb taking a direct object--for example, "Say something." "She found the cat."
   (eliminate utterly)obliterate vtrtransitive verb: Verb taking a direct object--for example, "Say something." "She found the cat."
  wipe out vtr phrasal sepphrasal verb, transitive, separable: Verb with adverb(s) or preposition(s), having special meaning, divisible--for example, "call off" [=cancel], "call the game off," "call off the game."
 Aniquiló su voluntad y terminó por anularla.
 He crushed (or: destroyed) her spirit and ended up destroying her.
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